QUESTIONS MO640 27th

Which of the statements is wrong, about the questions that arise in molecular evolution in which marcov model respond?
  

1. Correcting for multiple substitutions
2. Simulating sequence evolution
3. Estimating rates of evolution
4. Substitution scoring matrices 
5. The rate substitution, alpha is an explicit parameter for the model  

a) 1 and 2 are incorrect
b) 2, 3 and 4 are incorrect
c) only 5 is incorrect
d) 4 and 5 are incorrect
e) all are incorrect

by Shagali Huanca Vargas